Microcap Ledger

Tickers · $SPRO

Spero Therapeutics, Inc. $SPRO

By Microcap Ledger desk · CIK 0001701108

Facts as of . Built from SEC filings and our own data. Small caps move fast; check the latest filings.

Snapshot

Exchange
Nasdaq Global Select Market
Sector
Pharmaceutical Preparations
Headquarters
Cambridge, MA
Fiscal year end
December 31
Shares outstanding
58,234,827 [10-Q 2026-08-12]
as of 2026-08-07

Sources: [10-K 2026-03-26]

What the company doesAI summary of filing

Spero Therapeutics is a clinical-stage biopharmaceutical company that develops treatments for rare diseases and diseases with high unmet medical need. The company's primary focus is tebipenem HBr, an oral carbapenem antibiotic in development to treat complicated urinary tract infections in adults; in September 2022, Spero licensed tebipenem HBr exclusively to GlaxoSmithKline for development and commercialization outside certain Asian territories, receiving an upfront payment of $66 million and becoming eligible for up to $525 million in milestone payments plus tiered royalties on net sales. Spero has not generated revenue from product sales and remains pre-revenue, though it receives milestone payments from its GSK collaboration and previously received government funding. The company discontinued development of two earlier-stage programs, SPR206 and SPR720, in 2025 to focus resources on supporting GSK's FDA approval efforts for tebipenem HBr. [10-K 2026-03-26]

Segments: Tebipenem HBr

Financial health

From XBRL company facts (USD)
PeriodRevenueNet incomeOperating cash flowCashFiling
6 months to Jun 2026$258.0K−$16.75M $10.51M$50.77M[10-Q 2026-08-12]
FY ended Dec 2025$66.80M$8.57M −$12.62M$40.27M[10-K 2026-03-26]
FY ended Dec 2024$47.98M−$68.57M −$23.44M$52.89M[10-K 2026-03-26]

Capital structure and dilution

Summary only. How these instruments work: Dilution & financing desk.

Share count
DateShares outstandingFiling
2024-11-0654,518,165[10-Q 2024-11-14]
2025-03-2155,900,641[10-K 2025-03-27]
2025-05-0155,910,641[10-Q 2025-05-13]
2025-08-0556,275,225[10-Q 2025-08-12]
2025-11-0656,339,295[10-Q 2025-11-13]
2026-03-2057,891,493[10-K 2026-03-26]
2026-05-0157,901,493[10-Q 2026-05-13]
2026-08-0758,234,827[10-Q 2026-08-12]
Shelf registration
S-3 filed 2026-08-28; declared effective 2026-09-10 [S-3 2026-08-28]

Listing status

Current status: 1 Form 8-K Item 3.01 filing(s) in the last 24 months, most recent 2025-02-28. Item 3.01 covers delisting notices, failures to meet a listing rule and listing transfers; read the filing for which one.

DateEventDetailsDeadlineFiling
2025-02-288-K Item 3.01Notice of delisting or failure to satisfy a continued listing rule or standard; or transfer of listing—[8-K 2025-02-28]

More on deficiency notices and uplistings: Listing status desk.

Who owns it

Recent Form 4 transactions
DateInsiderTypeSharesPriceFiling
2026-08-03Zack Debragrant162,311—[4 2026-08-06]
2026-06-23Deshpande Milindgrant10,000—[4 2026-06-25]
2026-06-23Tregoning Kathleengrant10,000—[4 2026-06-25]
2026-06-23Smith Cynthiagrant10,000—[4 2026-06-25]
2026-06-23Vink Patrick V.J.J.grant10,000—[4 2026-06-25]
2026-06-23Thomas Frank Egrant10,000—[4 2026-06-25]
2026-06-23Jackson Scott Thomasgrant10,000—[4 2026-06-25]
2026-06-23Pottage John C Jrgrant10,000—[4 2026-06-25]

Catalysts and calendar

Facts as of . Small caps move fast; check the latest filings.